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成人左心房扩大(LAE)是心房颤动、卒中、充血性心力衰竭以及心原性死亡等多种心血管不良事件的独立预测因子。多数患者早期临床表现不明显,可能仅表现为非特异性症状,如气促、轻度呼吸困难,或仅表现出基础疾病的症状特征。因此,对LAE的早期识别和管理显得尤为重要。本文通过回顾左心房的解剖、LAE的病理生理机制及临床表现,探讨其诊断和管理策略,并达成专家共识,为提高成人LAE的临床管理提供参考依据。
Abstract:Left atrial enlargement(LAE) in adults is an independent predictor of various adverse cardiovascular events, including atrial fibrillation, stroke, congestive heart failure, and cardiac death. In most patients, early-stage clinical manifestations are nonspecific, potentially presenting only as mild dyspnea, exertional breathlessness, or symptoms attributable to underlying comorbidities. Consequently, early detection and management of LAE are of critical importance. This article reviews the anatomy of the left atrium, the pathophysiological mechanisms of LAE, and its clinical manifestations, while also discussing diagnostic approaches and therapeutic strategies, and reaches a consensus among experts to provide a reference for improving the clinical management of LAE in adults.
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中图分类号:R541.75
引用信息:
[1]湖北省基层医学联盟 ,湖北省基层医学联盟心血管专委会 ,华中科技大学同济医学院附属梨园医院 ,等.成人左心房扩大管理专家共识[J].巴楚医学,2025,8(04):1-10.
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