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目的:分析胡蜂蛰伤患者发生急性肾损伤(AKI)的影响因素,为临床早期诊断和治疗提供参考。方法:回顾性分析我院2014年1月-2020年9月救治的217名胡蜂蜇伤患者,收集患者的临床资料和实验室检查结果。采用Logistic回归分析其影响因素,采用受试者工作(ROC)曲线分析影响因素的诊断预测价值。结果:通过Logistic回归分析筛选出胡蜂蛰伤导致AKI的独立影响因素为蛰伤至就诊时长,丙氨酸转氨酶(ALT)、白细胞(WBC)、肌酸激酶(CK)和肌红蛋白(Myo)值,以上因素均与AKI的发生呈正相关(均Pfor trend<0.001),其联合诊断有较高的诊断预测效能[AUC=0.899 (95%CI:0.851～0.936),P<0.001]。结论:蛰伤至就诊时长、ALT、WBC、CK和Myo是胡蜂蛰伤发生AKI的独立影响因素,各危险因素联合有较高的诊断预测价值和临床指导意义。
Abstract：Objective:To analyze the influencing factors for acute kidney injury(AKI)induced by wasp stings,and provide reference for early diagnosis and treatment.Methods:A total of 217 patients with wasp sting treated in our hospital from January 2014 to September 2020 were retrospectively analyzed.Logistic regression was used to evaluate the influencing factors.Receiver operating characteristic(ROC)curve was used to estimate the diagnostic predictive value of these influencing factors.Results:The results of logistic regression analysis suggested that the independent influencing factors of AKI caused by wasp sting were hospital admission time,alanine aminotransferase(ALT),white blood cell(WBC),creatine kinase(CK)and myoglobin(Myo),all of which were positively correlated with the occurrence of AKI(all P for trend<0.001).The combined diagnosis of them had a highly diagnostic predictive efficiency [AUC=0.899(95%CI:0.851-0.936),P<0.001].Conclusion:Hospital admission time,ALT,WBC,CK and Myo are independent influencing factors for AKI caused by wasp stings.The combination of these risk factors has highly diagnostic predictive value and clinical guiding significance.
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基本信息:
中图分类号:R692;R646
引用信息:
[1]田飞,张蓉,刘静兰,等.胡蜂蜇伤致急性肾损伤的危险因素分析[J].巴楚医学,2021,4(04):54-59.
基金信息:
湖北省卫生计生西医类重点项目（No:WJ2015MA025）; 宜昌市医疗卫生科研项目（No:A19-301-02）
2020-10-29
2020
2021-01-07
2021-03-04
2021
1
2021-12-30
2021-12-30