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目的:采用Meta分析系统评价中西医结合治疗包虫病的疗效和安全性。方法:计算机检索中国知网(CNKI)、万方(Wanfang)、维普(VIP)、PubMed、中国生物医学文献(CBM)、中国临床试验注册中心、Cochrane图书馆数据库中关于中西医治疗包虫病的随机对照研究(RCTs)。两名研究者独立筛选符合纳入标准的研究,评估其研究质量,并提取资料。采用RevMan 5.3对上述数据行Meta分析。结果:共纳入4项随机对照试验,344例患者。经Meta分析显示,中西医结合治疗组较单纯西药组的临床有效率更高、不良反应发生率更低,且差异均具有统计学意义(均P<0.01)。结论:中西医结合治疗包虫病较单纯西医治疗具有一定的疗效优势和较高的安全性。
Abstract：Objective:To systematically evaluate the efficacy and safety of the combined treatment strategy of traditional Chinese medicine and western medicine in human echinococcosis.Methods:The database including CNKI,Wanfang,VIP,Pubmed,CBM,ChiCTR and Cochrane library were electronically searched for randomized controlled trials(RCTs)on the treatment of echinococcosis with traditional Chinese medicine and western medicine.Studies meeting the inclusion criteria were selected by two independent researchers,followed by quality evaluation.Data were extracted and meta-analyzed by the Revman 5.3 software.Results:A total of 4 RCTs involving 344 patients were included.The results of meta-analysis indicated that the clinical efficacy was increased,incidence of adverse reaction was decreased by combined treatment strategy of the traditional Chinese medicine and western medicine when compared to the treatment of western medicine alone,both with statistically differences(both P<0.01).Conclusion:Compared with treatment of western medicine alone,the combined treatment of Chinese and western medicine exerts certain therapeutic advantage and better safety for echinococcosis.
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基本信息:
中图分类号:R532.32
引用信息:
[1]廖原,许军英,邢稚坤,等.中西医结合治疗包虫病临床疗效和安全性的Meta分析[J].巴楚医学,2021,4(03):91-95.
基金信息:
国家自然科学基金项目（No:82060297,81760371,81760570）; 兵团科技发展专项资金项目（No:2018CB017,2019AB031）; 自治区研究生科研创新项目（No:XJ2020G121）
2021-09-30
2021-09-30