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目的:探讨复方紫草油局部外用治疗肛肠疾病术后湿疹的临床疗效与安全性。方法:将86例肛肠疾病术后继发肛周湿疹的患者随机分成治疗组和对照组,两组均予基础治疗,治疗组加用复方紫草油外敷皮损局部,对照组加用地奈德乳膏外涂。观察两组治疗1～2周的效果及停药1周的复发情况及住院时间。结果:经过1～2周治疗,两组患者肛周皮损、瘙痒感和渗出均有不同程度消退,两组的治愈率和总有效率差异无明显统计学意义(P>0.05)。停药1周后,对照组11例出现不同程度的肛周皮肤红肿、皮疹、渗出或瘙痒,治疗组1例出现肛周皮肤红肿,差异有统计学意义(P<0.05)。与对照组相比,治疗组住院时间明显缩短(P<0.05)。结论:复方紫草油外敷治疗肛周继发性湿疹疗效确切,不良反应少、复发率较低且能有效缩短住院时间,值得在临床中推广应用。
Abstract：Objective:To explore the clinical efficacy and safety of compound radix arnebiae oil for topical eczema after anorectal surgery.Methods:A total of 86 cases with perianal eczema after anorectal surgery were randomly divided into the treatment group and the control group.On the basis of routine therapy,cases in the treatment group were dealed with compound radix arnebiae oil for topical skin lesions,and the control group with desonide cream.The clinical efficacy after 1 to 2 weeks of treatment,the recurrence after 1 week since drug withdrawal and the hospital stays were observed and recorded.Results:After treatment for 1 to 2 weeks,the skin lesion,itch sensation and exudation of perianal skin were disappeared in different degrees,with no significant difference in cure rate and total effective rate between the two groups(P>0.05).After 1 week since drug withdrawal,there were 11 cases performed various degree of perianal skin redness,rash,exudation or itching in the control group,whereas only 1 case had perianal skin redness in the treatment group,with a significant difference(P <0.05).Compared with the control group,the hospital stay was obviously shortened in the treatment group(P<0.05).Conclusion:The external application of compound radix arnebiae oil is safe and effective in the treatment of perianal secondary eczema,with less recurrence and side effects,which can shorten hospital stay and is worthy of clinical promotion.
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基本信息:
中图分类号:R275.9
引用信息:
[1]朱妮,易文,姚宇宙,等.复方紫草油治疗肛肠疾病术后湿疹的临床研究[J].巴楚医学,2019,2(01):37-40.
2019-03-30
2019-03-30