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目的:探讨冷圈套联合黏膜下注射美兰溶液完整切除结直肠微小型息肉的临床应用价值。方法:选取2020年3月～2021年3月在本院治疗的112例结直肠息肉切除患者,采用简单随机分组分为观察组和对照组,每组各56例。对照组患者采用冷圈套切除治疗,观察组在对照组基础上联合黏膜下注射美兰溶液处理。比较两组一般资料、息肉治疗情况、并发症发生率和术后半年息肉检出率。结果:观察组手术时间为(3.46±0.48)min,长于对照组的(3.24±0.66)min(P<0.05)。观察组组织学完全切除率为89.29%,高于对照组的75.00%(P<0.05)。术后半年观察组息肉检出率为1.79%,明显低于对照组的14.29%(P<0.05)。结论:冷圈套联合黏膜下注射美兰溶液治疗结直肠微小息肉可有效提升组织学完整切除率,并降低术后半年息肉检出率。
Abstract：Objective:To explore the clinical application value of cold snare resection combined with submucosal injection of methylene blue solution in the treatment of colorectal micro-polyps.Methods:A total of 112 patients treated in our hospital between March 2020 and March 2021 were enrolled.They were divided into the observation group and the control group using simple random grouping method,with 56 cases in each group.The patients in the control group were treated with cold snare resection.The patients in the observation group were treated with submucosal injection of methylene blue solution in addition to cold snare resection.The general data,treatment of polyps,incidence of complications,and polyp detection rate at6 months after surgery were compared between two groups.Results:The operation time in the observation group was longer than that in the control group(3.46±0.48 vs 3.24±0.66)(P<0.05).The histological complete resection rate in the observation group was higher than that in the control group(89.29% vs75.00%)(P <0.05).The polyp detection rate at 6 months after surgery was significantly lower in the observation group than that in the control group(1.79% vs 14.29%)(P<0.05).Conclusion:Cold snare resection combined with submucosal injection of methylene blue solution could increase histological complete resection rate,and decrease polyp detection rate at 6 months after surgery.
[1]谢娇，王雯．结肠镜息肉切除术及其相关技术[J]．临床消化病杂志，2019,31(4):67-71．
[2]吴伟，王海浪．电子结肠镜下冷圈套切除术治疗结直肠小息肉的效果[J]．安徽医学，2020,41(9):93-96．
[3]罗哲，浦江，王晓辉，等．结直肠息肉内镜下黏膜切除术后迟发出血的临床特征及危险因素分析[J]．解放军医学杂志，2019,44(9):769-773．
[4]刘霞，张玲，吉鹏飞．冷圈套治疗结直肠（微）小息肉的临床效果研究[J]．现代消化及介入诊疗，2020,25(11):1454-1459．
[5]谢娇，王雯，李达周，等．冷圈套联合黏膜下注射对结直肠（微）小息肉的完整切除率的研究[J]．中华胃肠内镜电子杂志，2019,6(1):1-6．
[6]王妍，李欣，张蕾，等．冷圈套与热圈套切除结直肠小息肉的病例对照研究[J]．中华医学杂志，2018,98(34):2732-2736．
[7]胡阳，欧阳文，刘贞，等．结肠镜下高频电凝电切术与冷圈套切术治疗结肠微小息肉效果对比[J]．山东医药，2020,60(1):64-66．
[8]刘婧，卢静怡，杨兰芳，等．内镜下冷圈套器和热圈套器切除结直肠小息肉疗效和安全性研究的Meta分析[J]．中国内镜杂志，2020,26(11):7-13．
[9]中华医学会消化病学分会．中国结直肠肿瘤筛查、早诊早治和综合预防共识意见（一）[J]．胃肠病学，2011,16(11):666-675．
[10]刘宇英，伍民庆，李艳红，等．健康体检人群结直肠息肉患病情况及临床特征[J]．实用医学杂志，2019,35(20):3239-3242．
[11]陈宏达，代敏．中国结直肠癌预防和控制的思考[J]．中华流行病学杂志，2020,41(10):1627-1632．
[12]王成龙，王颢，赵子夜，等．上海某三甲医院结直肠癌相对无症状人群结肠镜检查中息肉与癌检出率现状及影响因素分析[J]．结直肠肛门外科，2019,25(2):131-136．
[13]陈建华，施宏，陈素玉，等．注气与注水肠镜下结直肠息肉的内镜形态与病理关系的比较[J]．中国肿瘤临床，2020,47(5):26-30．
[14]刘伟，王水芳，牟一，等．内镜下冷圈套器治疗大肠息肉42例临床分析[J]．中华消化内镜杂志，2014,31(9):519-521．
[15]崔月，李胜昔．冷圈套切除结直肠小息肉的临床效果[J]．中国当代医药，2020,27(23):61-64．
[16]姚毓洲，张耿坤，李采霞．常规内镜和色素内镜对早期食管癌，胃癌及癌前病变的诊断价值研究[J]．现代消化及介入诊疗，2020,25(5):124-126．
[17]Tate D J,Awadie H,Bahin F F,et al.Wide-field piecemeal cold snare polypectomy of large sessile serrated polyps without a submucosal injection is safe[J].Endoscopy,2018,50(3):248-252．
[18]Abe Y,Nabeta H,Koyanagi R,et al.Extended cold snare polypectomy for small colorectal polyps increases the R0resection rate[J].Endosc Int Open,2018,6(2):E254-E258．
[19]O'Connor S A,Brooklyn T N,Dunckley P D,et al.High complete resection rate for pre-lift and cold biopsy of diminutive colorectal polyps[J].Endosc Int Open,2018,6(2):E173-E178．
[20]张海涛．美兰双氧水混合液在直肠癌Dixcon术中应用87例临床分析[J]．中国实用医药，2016,11(18):175-176．
[21]徐威，胡学军，姚平，等．内镜黏膜冷切除术和热切除术在结直肠6~10 mm无蒂息肉治疗中的疗效对比[J]．中国临床医学，2020,27(6):1002-1006.
基本信息:
中图分类号:R656.9;R657.1
引用信息:
[1]朱胜,胡林,陆佳燕.冷圈套联合美兰溶液黏膜下注射治疗结直肠微小息肉的临床价值[J].巴楚医学,2021,4(03):32-35.
基金信息:
常熟市科技局民生科技技术支持项目（No:cswzd202048）
2021-09-30
2021-09-30