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目的：观察角膜地形图引导的经上皮准分子激光角膜切削术(Trans-PRK)治疗非光学区角膜穿通伤术后角膜不规则散光的效果。方法：选取9例9眼角膜穿通伤缝合瘢痕在光学中心外的患者，使用光治疗性角膜切削术去除上皮后，采用角膜地形图引导Trans-PRK进行屈光不正治疗，观察手术前后患者的视力、屈光状态、眼压、角膜雾浊及角膜规则性的变化。结果：所有患者术后角膜恢复良好，术后1年角膜形态趋于稳定。患者裸眼视力从术前0.28±0.18上升至术后0.56±0.19,最佳矫正视力由0.60±0.25提高至0.91±0.21,角膜ISV值由53.33±14.28降低至28.11±6.25,Irregularities值由0.070±0.014降低至0.039±0.011,差异均有统计学意义(均P<0.01)。结论：Trans-PRK能有效提高角膜穿通伤术后不规则散光患者的视力及视觉质量，改善角膜表面的规整性，提高眼部舒适度。
Abstract：Objective: To observe the effect of transepithelial photorefractive keratectomy(Trans-PRK) guided by corneal topographic map in the treatment of irregular astigmatism after corneal perforation injury in non-optical areas. Methods: There were 9 patients(9 eyes) with suture scar outside the optical center selected. Epithelium was removed by phototherapeutic keratectomy. Corneal topographic map was used to guide Trans-PRK for ametropia treatment. The changes of visual acuity, refractive state, intraocular pressure, corneal haze and corneal regularity were observed before and after surgery. Results: All patients had good recovery after surgery, and the corneal morphology tended to be stable 1 year after surgery. The naked eye visual acuity increased from 0.28±0.18 to 0.56±0.19, the best corrected visual acuity increased from 0.60±0.25 to 0.91±0.21, the corneal ISV decreased from 53.33±14.28 to 28.11±6.25, and the irregularities value decreases from 0.070±0.014 to 0.039±0.011, with statistically significant differences(all P<0.01). Conclusion: Trans-PRK can effectively increase the visual acuity and visual quality, improve the regularity of corneal surface, and enhance eye comfort in patients with irregular astigmatism after corneal perforation injury.
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基本信息:
中图分类号:R779.6;R778.13
引用信息:
[1]莫纯坚,王红俊,梁亮,等.角膜地形图引导的Trans-PRK治疗角膜穿通伤术后不规则散光的临床观察[J].巴楚医学,2023,6(03):105-109.
基金信息:
国家自然科学基金项目(No:81770920)
2023-09-30
2023-09-30