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宫颈癌是世界上发病率和死亡率位居第四的肿瘤,也是中国女性最常见的肿瘤之一。为改善宫颈癌患者的预后,提高患者的生存率,迫切需要寻找新的治疗靶点及预后标志物。近年来,研究发现长链非编码RNA(LncRNA)在宫颈癌、正常组织和良性肿瘤中的表达存在差异,提示LncRNA可能参与调节宫颈癌的发生和发展。目前已发现数种LncRNA与宫颈癌的发生、侵袭和进展有关。本文拟对LncRNA在宫颈癌发生发展中的具体作用、分子机制以及潜在临床应用作一综述。
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基本信息:
中图分类号:R737.33
引用信息:
[1]杨月楠,黄乔,杨自为.LncRNA与宫颈癌的研究进展[J].巴楚医学,2022,5(04):117-120.
基金信息:
中国博士后基金面上项目(No:2017M612816); 宜昌市医疗卫生科研项目(No:A19-301-01)
2022-12-26
2022-12-26