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目的：分析经典型热射病患者的临床特征及死亡风险因素，为早期评估患者预后提供参考。方法：回顾性分析2020年1月—2023年12月三峡区域3家医院收治的130例经典型热射病患者的临床资料，分为存活组(n=109)和死亡组(n=21),采用单因素及多因素Logistic回归分析经典型热射病患者死亡的独立危险因素，并绘制受试者工作特征(ROC)曲线。结果：多因素Logistic回归分析结果显示，心率增快(OR=1.056,95%CI:1.018,1.095)和凝血酶原时间(PT)延长(OR=1.429,95%CI:1.009,2.024)是经典型热射病患者死亡的独立危险因素(均P<0.05)。ROC曲线显示，心率、PT及联合预测的曲线下面积分别为0.803、0.876和0.910。联合预测的敏感度和特异度分别为90.48%和83.49%。结论：心率增快和PT延长是经典型热射病患者死亡的独立危险因素，可作为评估经典型热射病患者预后的参考指标。
Abstract：Objective: To analyze the clinical characteristics and risk factors for mortality in patients with classic heat stroke in order to provide reference indicators for early prognosis assessment. Methods: A multicenter retrospective study was performed from January 2020 to December 2023 in three hospitals of Three Gorges region. A total of 130 classic heat stroke patients were enrolled. According to prognosis, those patients were divided into survival group(n=109) and death group(n=21). The risk factors for death in classic heat stroke patients were investigated by univariate and multivariate Logistic regression analysis. Receive operating characteristic(ROC) curves were constructed to evaluate the predictive performance. Results: Multivariate Logistic regression analysis indicated that elevated heart rate(OR=1.056, 95%CI: 1.018, 1.095) and prolonged prothrombin time(PT)(OR=1.429, 95%CI: 1.009, 2.024) were independent risk factors for mortality in patients with classic heat stroke(both P<0.05). The areas under the ROC curves for heart rate, PT, and the combined model were 0.803, 0.876, and 0.910, respectively. The combined model demonstrated a sensitivity of 90.48% and a specificity of 83.49%. Conclusion: Increased heart rate and prolonged PT are independent predictors of mortality in patients with classic heat stroke and may serve as valuable clinical indicators for assessing disease severity and prognosis.
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基本信息:
中图分类号:R594.1
引用信息:
[1]鲁光锐,杨思雨,周法庭,等.三峡区域经典型热射病死亡危险因素分析[J].巴楚医学,2025,8(04):51-57.
基金信息:
重庆市科卫联合重点项目(2024ZDXM024); 重庆市自然科学基金面上项目(CSTB2024NSCQ-MSX0873); 急诊医学重庆市重点实验室开放课题(2023KFKT03)
2025-12-30
2025-12-30