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2024, 02, v.7 103-110
经皮穴位电刺激预防老年患者术后谵妄的Meta分析
基金项目(Foundation): 白求恩公益基金会恩泽疼痛管理医学研究项目(No:ezmr2023-016)
邮箱(Email): 297242464@qq.com;
DOI:
发布时间: 2024-06-27
出版时间: 2024-06-27
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摘要:

目的:采用Meta分析评价经皮穴位电刺激(TEAS)在预防老年患者术后谵妄(POD)中的效果。方法:系统检索Pubmed、Cochrane Library、Web of Science、Embase、中国知网、万方和维普等数据库,收集建库至2023年8月30日关于TEAS治疗老年手术患者的随机对照试验(RCTs),采用RevMan 5.3软件进行Meta分析。结果:本研究共纳入22篇文献,共2 645例研究对象。Meta分析结果显示,TEAS能降低老年患者术后POD的发生率(RR=0.46,95%CI:0.38,0.56),接受骨科手术(RR=0.50,95%CI:0.40,0.63)、腹部手术(RR=0.41,95%CI:0.25,0.65)及肿瘤手术(RR=0.33,95%CI:0.19,0.57)的老年患者术后POD的发生率均显著下降(均P<0.001);TEAS术中全程(RR=0.39,95%CI:0.29,0.53)或延续到术后(RR=0.52,95%CI:0.36,0.75)可明显降低老年患者术后POD发生率。结论:TEAS可有效降低行骨科、腹部及肿瘤等手术的老年患者术后POD的发生,TEAS术中全程使用或延续到术后均能有效抑制老年患者术后POD的发生,值得临床推广应用。

Abstract:

Objective: To evaluate the effect of transcutaneous electrical acupoint stimulation(TEAS) in preventing postoperative delirium(POD) among elderly patients using meta-analysis. Methods: Databases such as PubMed, Cochrane Library, Web of Science, Embase, CNKI, Wanfang, and VIP were systematically searched to collect randomized controlled trials(RCTs) on TEAS for the treatment of elderly surgical patients from the establishment of the databases to August 30, 2023. Meta-analysis was performed using RevMan 5.3 software. Results: A total of 22 studies with 2 645 participants were included in this study. The meta-analysis showed that TEAS could reduce the incidence of POD in elderly patients(RR=0.46, 95%CI: 0.38,0.56). The incidence of POD in elderly patients undergwent orthopedic surgery(RR=0.50, 95%CI: 0.40,0.63), abdominal surgery(RR=0.41, 95%CI: 0.25,0.65), and tumor surgery(RR=0.33, 95%CI: 0.19,0.57) were significantly reduced(all P<0.001). TEAS applied throughout the intraoperative period(RR=0.39, 95%CI: 0.29,0.53) or continued postoperatively(RR=0.52, 95%CI: 0.36,0.75) could significantly reduce the incidence of POD in elderly patients. Conclusion: TEAS can reduce the incidence of POD in elderly patients undergoing orthopedic, abdominal, and tumor surgeries. The use of TEAS throughout the intraoperative period or continuation postoperatively can effectively suppress the occurrence of POD in elderly patients, which is worthy of clinical promotion and application.

参考文献

[1] 张琦.经皮穴位电刺激对老年胃肠手术患者术后谵妄的影响[D].大连:大连医科大学,2022.

[2] Swarbrick C J,Partridge J S L.Evidence-based strategies to reduce the incidence of postoperative delirium:a narrative review[J].Anaesthesia,2022,77(Suppl 1):92-101.

[3] 罗云根,曹江北.老年患者术后谵妄的研究进展[J].中华老年多器官疾病杂志,2023,22(10):783-786.

[4] Wildes T S,Mickle A M,Ben Abdallah A,et al.Effect of electroencephalography-guided anesthetic administration on postoperative delirium among older adults undergoing major surgery:the ENGAGES randomized clinical trial[J].JAMA,2019,321(5):473-483.

[5] Inouye S K,Westendorp R G J,Saczynski J S.Delirium in elderly people[J].Lancet,2014,383(9920):911-922.

[6] 王妮,龚勋,谭柏栋,等.右美托咪定、咪达唑仑和丙泊酚在ICU机械通气患者镇静治疗中的有效性和安全性:基于贝叶斯的网状Meta分析[J].巴楚医学,2021,4(1):69-80.

[7] Migirov A,Chahar P,Maheshwari K.Postoperative delirium and neurocognitive disorders[J].Curr Opin Crit Care,2021,27(6):686-693.

[8] Xu Y N,Ma Q Q,Du H M,et al.Postoperative delirium in neurosurgical patients:recent insights into the pathogenesis[J].Brain Sci,2022,12(10):1371.

[9] Li S Y,Jiang H L,Liu W,et al.Transcutaneous electrical acupoint stimulation for the prevention of perioperative neurocognitive disorders in geriatric patients:a systematic review and meta-analysis of randomized controlled trials[J].Medicine (Baltimore),2022,101(50):e32329.

[10] Zhang T T,Ou L,Chen Z H,et al.Transcutaneous electrical acupoint stimulation for the prevention of postoperative cognitive dysfunction:a systematic review and meta-analysis[J].Front Med (Lausanne),2021,8:756366.

[11] Wang D,Shi H S,Yang Z G,et al.Efficacy and safety of transcutaneous electrical acupoint stimulation for postoperative pain:a meta-analysis of randomized controlled trials[J].Pain Res Manag,2022,2022:7570533.

[12] 葛月萍,郑娟丽,余燕华.穴位电刺激对老年肾虚血瘀型髋关节置换患者术后康复的影响[J].护理与康复,2023,22(7):50-52.

[13] 吴洪燕,高鸿,米智华,等.经皮穴位电刺激对老年衰弱患者术后谵妄的影响[J].中华麻醉学杂志,2021,41(6):723-726.

[14] Gao F,Zhang Q,Li Y N,et al.Transcutaneous electrical acupoint stimulation for prevention of postoperative delirium in geriatric patients with silent lacunar infarction:a preliminary study[J].Clin Interv Aging,2018,13:2127-2134.

[15] Higgins J P T,Altman D G,G?tzsche P C,et al.The Cochrane Collaboration’s tool for assessing risk of bias in randomised trials[J].BMJ,2011,343:d5928.

[16] 雒晓燕,崔仁善,许秀梅,等.基于“互联网+” 的护理干预对癌症患者疼痛影响的Meta分析[J].中华护理杂志,2023,58(9):1056-1062.

[17] 韦晨浦,郝宁,刘洁,等.电刺激“鬼穴” 复合气管内全麻对老年患者全膝关节置换术后谵妄的观察[J].吉林中医药,2022,42(3):362-365.

[18] 王志刚.电针对围术期神经认知障碍的影响及相关机制研究[D].石家庄:河北医科大学,2022.

[19] 王麒,周瑞玲,丁玲玲,等.电针与经皮穴位电刺激对老年患者术后谵妄的影响[J].中国中西医结合外科杂志,2022,28(4):485-490.

[20] 刘稳.经皮穴位电刺对肺癌根治术老年患者术后谵妄发生率及早期康复的影响[J].肿瘤基础与临床,2019,32(5):400-404.

[21] 杜文文,郑建宇,黄敏贞,等.经皮穴位电刺对肺癌根治术老年患者术后谵妄发生率的影响[J].安徽医专学报,2022,21(3):30-31.

[22] 秦琳涵.经皮穴位电刺激对老年腹腔镜手术患者术后睡眠质量的影响[D].石家庄:河北医科大学,2021.

[23] 钱志伟.经皮穴位电刺激对老年脊柱手术患者术后谵妄的影响[D].苏州:苏州大学,2018.

[24] 史会建,李伟伟,张业峰,等.经皮穴位电刺激对老年脊柱术后睡眠的影响[J].中国矫形外科杂志,2022,30(22):2045-2049.

[25] 张瑜玲.经皮穴位电刺激对老年髋部骨折患者术后谵妄的影响[D].广州:广州中医药大学,2021.

[26] 常明智.经皮穴位电刺激对睡眠障碍老年全髋关节置换术患者术后疲劳及神经认知障碍的影响[D].大连:大连医科大学,2021.

[27] 徐贤亮,黄仙保,余奕军,等.经皮穴位电刺激辅助麻醉对老年腰椎手术术后应激反应及谵妄的影响[J].中国医学创新,2022,19(16):53-57.

[28] 钱佳微,戴兴芹,詹晓雁,等.经皮穴位电刺激联合情志疗法在老年关节置换术后亚谵妄综合征中的应用[J].护理与康复,2022,21(4):28-31.

[29] 丁玲玲,寇士顺,王麒,等.经皮穴位电刺激联合右美托咪啶对老年患者术后谵妄的影响[J].中国医药导报,2020,17(4):123-126.

[30] 黄俊.经皮穴位电刺激神门、内关穴对老年髋关节置换术患者睡眠质量及术后谵妄的影响[D].长沙:湖南师范大学,2020.

[31] 曹莉,陈振华,杨建新,等.经皮穴位电刺激预处理治疗老年全髋关节置换术后谵妄的临床研究[J].中西医结合心脑血管病杂志,2022,20(2):348-352.

[32] Ding L L,Ning J Q,Guo Y H,et al.The preventive effect of transcutaneous electrical acupoint stimulation on postoperative delirium in elderly patients with time factors:a randomized trial[J].J Integr Complement Med,2022,28(8):689-696.

[33] Zhang Y F,Gong L R,Zhang Y,et al.Effect of transcutaneous acupoint electrical stimulation on urinary retention and urinary ATP in elderly patients after laparoscopic cholecystectomy:a prospective,randomized,controlled clinical trial[J].Clin Interv Aging,2022,17:1751-1760.

[34] Fan Q Q,Lei C,Wang Y H,et al.Transcutaneous electrical acupoint stimulation combined with auricular acupressure reduces postoperative delirium among elderly patients following major abdominal surgery:a randomized clinical trial[J].Front Med (Lausanne),2022,9:855296.

[35] Evered L A,Chan M T V,Han R Q,et al.Anaesthetic depth and delirium after major surgery:a randomised clinical trial[J].Br J Anaesth,2021,127(5):704-712.

[36] 陈薪宇.经皮穴位电刺激影响老年人全麻术后认知:一项系统评价和Meta分析[D].长春:吉林大学,2023.

[37] Chen J B,Tu Q,Miao S,et al.Transcutaneous electrical acupoint stimulation for preventing postoperative nausea and vomiting after general anesthesia:a meta-analysis of randomized controlled trials[J].Int J Surg,2020,73:57-64.

[38] Guo F,Yan Y T,Sun L,et al.Transcutaneous electrical acupoint stimulation for preventing postoperative delirium:a meta-analysis[J].Neuropsychiatr Dis Treat,2023,19:907-920.

[39] Lin G X,Wang T,Chen M H,et al.Serum high-mobility group box 1 protein correlates with cognitive decline after gastrointestinal surgery[J].Acta Anaesthesiol Scand,2014,58(6):668-674.

[40] Yang H,Liu H,Zeng Q,et al.Inhibition of HMGB1/RAGE-mediated endocytosis by HMGB1 antagonist box A,anti-HMGB1 antibodies,and cholinergic agonists suppresses inflammation[J].Mol Med,2019,25(1):13.

[41] 于波,丁玲玲,陆斌,等.经皮穴位电刺激对腹腔镜手术全麻患者脑保护及应激作用的研究[J].陕西中医,2020,41(2):241-244.

[42] Huang K Y,Liang S,Chen L,et al.Transcutaneous electrical acupoint stimulation for the prevention of postoperative delirium in elderly surgical patients:a systematic review and meta-analysis[J].Front Aging Neurosci,2023,15:1046754.

基本信息:

中图分类号:R246

引用信息:

[1]田书梅,魏永婷,席祖洋,等.经皮穴位电刺激预防老年患者术后谵妄的Meta分析[J].巴楚医学,2024,7(02):103-110.

基金信息:

白求恩公益基金会恩泽疼痛管理医学研究项目(No:ezmr2023-016)

发布时间:

2024-06-27

出版时间:

2024-06-27

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